Insulin, 1955: A Physician’s Read on the First Protein Sequence
Sanger's insulin papers of 1951 to 1955, read as a physician: the method, the species comparison, what the sequence could not show, and the clinical line to analogs and C-peptide.
Oxytocin, 1953: A Physician’s Read on the First Synthetic Peptide Hormone
The first synthetic peptide hormone, read from the papers: the 1953 synthesis, the 1954 head-to-head test in postpartum women, the limits, and the line to desmopressin and carbetocin.
Insulin, 1922: A Physician’s Read on the First Peptide Medicine
The first clinical use of insulin, read from the 1922 paper: a failed first injection, a purification fix, a treatment and not a cure, and the line to today's research.